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Writer's pictureMuriel Wallace-Scott

Is gluten Only An Issue If You Have Coeliac Disease?


Gluten, a protein found in wheat, barley, and rye, has gained considerable attention in recent years due to its potential impact on health. While gluten is well-tolerated by most people, some individuals may experience adverse effects when consuming gluten-containing foods.


In this blog post, we will explore different reasons why gluten may negatively impact your health and discuss various conditions associated with gluten sensitivity.

  • Celiac Disease: Celiac disease is an autoimmune disorder triggered by the ingestion of gluten. In individuals with celiac disease, the immune system reacts to gluten, damaging the lining of the small intestine. This immune response leads to inflammation, villous atrophy, and nutrient malabsorption. Common symptoms include gastrointestinal issues like abdominal pain, diarrhea, bloating, as well as fatigue, weight loss, and nutrient deficiencies.

  • Non-Celiac Gluten Sensitivity: Some individuals may experience symptoms similar to those of celiac disease when consuming gluten, but without the characteristic intestinal damage or autoimmune response. This condition is known as non-celiac gluten sensitivity (NCGS). Symptoms of NCGS can include abdominal pain, bloating, diarrhea or constipation, fatigue, headaches, brain fog, and joint pain.

  • Wheat Allergy: A wheat allergy is an immune-mediated reaction to specific proteins in wheat, including gluten. Unlike celiac disease or NCGS, a wheat allergy involves an immediate immune response, often affecting the skin, respiratory system, or gastrointestinal tract. Symptoms can range from mild, such as hives or itching, to severe, including difficulty breathing or anaphylaxis.

  • FODMAPs: FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) are a group of carbohydrates that can trigger digestive symptoms in some individuals, including those with irritable bowel syndrome (IBS). Wheat-based products are a common source of FODMAPs, and it is believed that it is the FODMAP content, rather than gluten itself, that causes symptoms in these individuals.

  • Other Sensitivities or Intolerances: It is possible for individuals to have sensitivities or intolerances to other components present in gluten-containing grains, such as specific proteins or carbohydrates. For example, individuals with a sensitivity to amylase trypsin inhibitors (ATIs), a group of proteins found in wheat, may experience gut and systemic inflammation when consuming gluten-containing foods.

  • Glyphosate is a widely used herbicide, most commonly known as the active ingredient in the weed killer Roundup. Some studies suggest that glyphosate may have potential effects on gut health. One proposed mechanism is that glyphosate can disrupt the balance of beneficial bacteria in the gut, potentially leading to dysbiosis (an imbalance of gut microbiota). This disruption in the gut microbiome has been linked to various health issues, including digestive disorders, immune system dysfunction, and inflammation. Glyphosate has also been proposed to disrupt the integrity of the gut barrier, potentially contributing to increased intestinal permeability, commonly known as "leaky gut." Leaky gut refers to a condition where the lining of the intestines becomes more permeable, allowing substances to leak into the bloodstream and potentially triggering an immune response and inflammation.

  • Personal Sensitivities: Lastly, it is important to acknowledge that some individuals may experience adverse reactions to gluten based on their unique biochemistry or individual sensitivities. While these reactions may not fit into established categories, it is essential to listen to your body and seek professional guidance if you suspect gluten may be negatively impacting your health.


While gluten is well-tolerated by the majority of individuals, there are various reasons why it may negatively impact your health in certain cases. Celiac disease, non-celiac gluten sensitivity, wheat allergy, FODMAPs, other sensitivities or intolerances, and personal sensitivities can all contribute to adverse reactions associated with gluten consumption. If you suspect gluten may be affecting your health, it is important to consult with a healthcare professional for proper evaluation, diagnosis, and guidance.

A personalised approach that considers your specific condition, symptoms, and individual needs will help you navigate your dietary choices and optimize your overall well-being.


Remember, understanding your body's unique response to gluten can empower you to make informed decisions about your health and lead a balanced, healthy lifestyle.

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